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U.S. Patents Held by Designed Nutritional Products

Designed Nutritional Products has been issued multiple U.S. patents covering methods of use for dietary indole compounds — a reflection of more than 30 years of original research and development in this category. These patents have expired but stand as a record of our pioneering role in bringing dietary indoles to the nutritional supplement industry.

2
U.S. Patents Issued
Both covering dietary indole compound applications
1992
Commercial Source Since
Original commercial source for I3C and dietary indole pioneer
Issued Patents

U.S. Patent Portfolio

The following U.S. patents were issued for methods of use involving 1H-indole-3-methanol (I3C) compounds. Both patents have expired. They are listed here as a record of the original research and development work behind our dietary indole ingredients.

U.S. Patent — Issued April 20, 1999
Treatment of Fibromyalgia and Related Disorders
Arffmann, et al. — USPTO Patent No. 5,895,787
5,895,787
Patent Number
Patent Abstract

A patent describing a method using 1H-indole-3-methanol compounds in relation to fibromyalgia-like complaints including fibromyalgia, chronic fatigue syndrome, and irritable bowel syndrome. The method comprises administering to the patient a 1H-indole-3-methanol compound.

This patent covers the application of I3C compounds in specialty wellness contexts. It represents early clinical research into dietary indole applications that was conducted in collaboration with Designed Nutritional Products. The patent has expired.
View on USPTO.gov →
Patent Details
Patent No.5,895,787
IssuedApril 20, 1999
InventorsArffmann et al.
Compound1H-Indole-3-methanol
StatusExpired
Related Ingredients
I3C → Ascorbigen → DIM →
Status Note
This patent has expired. It is listed as a record of the research and development history of dietary indole compounds at Designed Nutritional Products.
U.S. Patent — Issued September 2, 2003
Treatment of Premenstrual Syndrome and Menopause
Ellenberger, et al. — USPTO Patent No. 6,613,792
6,613,792
Patent Number
Patent Abstract

A patent describing a method using 1H-indole-3-methanol compounds (including 1H-indole-3-methanol and ascorbigen) in relation to premenstrual syndrome and menopausal symptoms. The method comprises administering the compound to the patient in a medically acceptable manner in a pharmaceutically effective amount.

This patent references both I3C and Ascorbigen as the active compounds and covers applications in women's wellness categories. It represents an important milestone in the clinical research history of dietary indoles. The patent has expired.
View on USPTO.gov →
Patent Details
Patent No.6,613,792
IssuedSeptember 2, 2003
InventorsEllenberger et al.
CompoundsI3C, Ascorbigen
StatusExpired
Related Ingredients
I3C → Ascorbigen →
Status Note
This patent has expired. It is listed as a record of the research and development history of dietary indole compounds at Designed Nutritional Products.
Our Ingredients

Interested in sourcing the ingredients behind these patents?

Designed Nutritional has been the original commercial source for I3C and an early pioneer in DIM and Ascorbigen since 1992. The ingredients covered by these patents are available in bulk for supplement brands, formulators, and contract manufacturers. Full COA provided with every order. CFR 117 compliant.

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About These Patents
Both patents have expired. They are listed here as a record of original research and development work — not as active intellectual property claims.
The patents describe methods, not ingredients. The underlying ingredients — I3C, Ascorbigen, and DIM — are freely available as dietary supplement ingredients under DSHEA.
They represent depth of research. Issued U.S. patents require rigorous scientific evidence. These filings reflect years of original research into dietary indole applications.
Structure/function claims apply. Published research referenced in these patents may be cited as supporting evidence for appropriate structure/function claims. Contact us for formulation and regulatory guidance.