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Hormone Balance · Antioxidant · Bulk Ingredient · Product No. 8001

Ascorbigen — Bulk Dietary Indole Supplier

ASC · CAS 8075-98-7

The most stable of the commercially available dietary indoles — requiring no refrigeration or light protection. Ascorbigen is a naturally occurring indole-vitamin C complex that supports healthy hormone metabolism and normal antioxidant activity.* Sourced from India, warehoused and tested in the USA. Available in bulk powder for supplement brands and formulators worldwide.

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CAS Number
8075-98-7
Chemical Formula
C₁₄H₁₅NO₇
Molecular Weight
305.28 g/mol
Purity (HPLC)
Min. 98%
Country of Origin
India
Regulatory Status
DSHEA Compliant
Ordering Information
Ascorbigen — Bulk Powder
FormPowder
Minimum Order1 kg
Shelf Life2 years
StorageBelow 50°C, no special requirements
PackagingCardboard box + plastic bag
Warehoused & testedUSA
PricingRequest a quote

COA provided with every order · SDS available on request

Full Technical Specifications

Certificate of Analysis — Specification Sheet

Physical & Chemical Properties
Product Number8001
AppearanceOff-white amorphous powder
IdentificationBy IR
Melting PointSinters at 65°C
Assay (HPLC Purity)Min. 98%
Molecular Weight305.28 g/mol
Country of OriginIndia
Warehoused & TestedUSA
Shelf Life2 years
StorageBelow 50°C, no special requirements
Heavy Metals Testing
Arsenic< 1 ppm
Cadmium< 1 ppm
Mercury< 1 ppm
Lead< 1 ppm
Microbiological Profile
Standard Plate Count< 10,000 cfu/g
Coliforms< 10 cfu/g
E. ColiNegative
SalmonellaNegative
Staph Coag (+)< 10 cfu/g
Yeast & Mold< 1,000 cfu/g
Formulation Benefits

Why formulators choose Ascorbigen

Ascorbigen is the most prevalent of the dietary indoles shown to have significant physiological activity and is considered the most stable commercially available dietary indole. Since 1992, Designed Nutritional has supplied Ascorbigen to supplement brands and formulators building products in hormone balance, antioxidant, immune support, and skin wellness categories. Sourced from India, warehoused and tested in the USA.

Ascorbigen is a naturally occurring indole-vitamin C complex formed from Indole-3-Carbinol (I3C) in the presence of ascorbic acid. It is produced naturally in cruciferous vegetable juices when cell walls are broken through chopping, chewing, or juicing. First identified in 1935 and isolated from Savoy cabbage juice in 1957, Ascorbigen may exhibit synergy with I3C. [Ref. 15, 18, 19]
Suggested Dosage Range
200 – 400 mg/day
Adults. Children may take up to ½ adult dosage.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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Hormone Balance*

Ascorbigen supports healthy hormone metabolism, including normal estrogen metabolism toward 2-Hydroxyestrone. Widely considered the most active dietary indole for hormone balance applications and is commonly formulated alongside I3C and DIM in women's wellness product lines.

Ref. [9] Michnovicz & Bradlow, 1991 · Ref. [13] Loub et al., 1975
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Antioxidant Activity*

Ascorbigen is a skin-permeable form of Vitamin C and supports normal antioxidant activity. As a vitamin C indole complex, it contributes to the body's natural antioxidant systems. Referenced in published research for its role in supporting normal cellular function.

Ref. [2] Bukin et al., 1987 · Ref. [3] Mukhanov et al., 1984
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Immune Function Support*

Ascorbigen supports normal immune function. Published research has examined its immunostimulatory properties. Commonly included in immune support formulations and wellness product lines targeting overall immune health.

Ref. [3] Mukhanov et al., 1984 · Ref. [4] Plikhtyak et al., 1988
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Skin Wellness*

As a skin-permeable form of Vitamin C, Ascorbigen supports normal skin conditioning and healthy skin function. Referenced in a Japanese patent for skin conditioning properties. Used in formulations targeting skin wellness and normal skin health maintenance.

Ref. [7] Fukushima & Toyoda, 1987 Japanese Patent
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Synergy with I3C & DIM

Ascorbigen may exhibit synergy with Indole-3-Carbinol and is considered by researchers to be a potentially essential component of dietary indole activity. Often formulated together with I3C and DIM in comprehensive hormone balance and dietary indole product lines.

Ref. [18] Chinoy, 1977 · Ref. [19] Kahatriya, 1977
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Superior Stability

Ascorbigen is the most stable of the commercially available dietary indoles. No refrigeration required. No protection from light required. Stable up to 50°C. Trace amounts of more reactive dietary indoles contribute to product color and are considered beneficial.

Product Specification — Designed Nutritional No. 8001
Packaging & Ordering

Available packaging options

01

Small Orders

Suitable for sampling, small-batch production, and R&D formulation work. Securely packaged to maintain product integrity during shipping.

Cardboard box with plastic bag · MOQ 1 kg
02

Bulk Orders

For production-scale orders. Contact us for bulk packaging options and pricing. We work with you to meet your production and logistics requirements.

Contact us for bulk quantities →
03

Custom Quantities

Need a specific quantity or custom arrangement? Contact us directly and we will work with you on packaging and logistics to fit your production needs.

Contact us for custom orders →
Synonyms & Alternate Names
  • Ascorbigen
  • 2-C-(1H-Indol-3-ylmethyl)-β-L-lyxo-3-hex-ulofuranosonic acid γ-lactone
  • Indole-vitamin C complex
  • Dietary Indole · CAS 8075-98-7
Classification & Regulatory
ClassificationDietary Indole
Regulatory StatusDSHEA Compliant
Facility RegistrationFDA Registered
GMP Standard21 CFR Part 117
Country of OriginIndia
Warehoused & TestedUSA
PatentsNone specific to Ascorbigen
Scientific References

Published Research

[1]McDanell, R. et al. 1987. Food and Chemical Toxicology 25: 363–368.
[2]Bukin, Y.V. et al. 1987. Khim IA 13: 539–545.
[3]Mukhanov, V.I. et al. 1984. Soviet Journal of Bioorganic Chemistry 10: 544–559.
[4]Plikhtyak, I.L. et al. 1988. Khim. Getcrotsikl. Sosdin. 131–132.
[5]Efimox, S.A. 1989. Antibiot. Khimioter 34: 125–129.
[6]Anonymous. 1978. Analysis and Research (Japan) 16: 546–550.
[7]Fukushima, S.; Toyoda, H. 1987. Japan Kokai Tokyo Koho Japanese Patent 62/155204 A2 [87/155204], July 10.
[8]Andrus, G.M.; Arffman, K. 1999. United States Patent 5,895,787, April 20.
[9]Michnovicz, J.J.; Bradlow, H.L. 1991. Nutrition and Cancer 16: 59–66. Also: Michnovicz, J.J.; Bradlow, H.L. 1990. Journal of the National Cancer Institute 82: 947–949.
[10]Sepkovic, D. et al. 1994. Steroids 59: 318–323.
[11]Bell, M.C. et al. 2000. Gynecologic Oncology 78: 123–129.
[12]Newfield, L. et al. 1993. Anticancer Research 13: 337–342.
[13]Loub, W.E.; Wattenberg, L.W.; Davis, D.W. 1975. Journal of the National Cancer Institute 54: 985–988.
[14]Preobrazhenskaya, M.N.; Korolev, A.M. 1992. Journal of the National Cancer Institute 84: 15, 1210–1211.
[15]Zeligs, M.A. 1998. Journal of Medicinal Food 1:2, 67–82.
[16]Ahmad, B. 1935. Biochemistry Journal 29: 275.
[17]Prochazka, Z. et al. 1957. Collection of Czechoslovakian Chemical Communications 22: 333, 654.
[18]Chinoy, N.J. 1977. Journal of Animal Morphology and Physiology 24: 173–185.
[19]Kahatriya, A.M. 1977. Journal of Animal Morphology and Physiology 24: 379–386.
Stability Note
Ascorbigen is the most stable of the commercially available dietary indoles. It requires neither refrigeration nor protection from light. Degradation will occur at temperatures in excess of 50°C. Trace amounts of more reactive dietary indoles contribute to product color and are considered beneficial.
Caution
Amounts in excess of recommended dosages may cause diarrhea.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. References cited are published third-party research provided for informational purposes only.